Aim

The integration of the new developments in protein crystallography, enzymology, computer simulation and modeling, and directed evolution research, in combination with high throughput technologies, offers great opportunities for generating new biocatalytic applications (Ghirlanda, 2008).

This requires a close cooperation between different disciplines centered on (i) organic chemistry (having extensive understanding of chemical reactions), (ii) structural enzymology (with expertise on enzyme-catalyzed reactions), as well as on (iii) bioprocess technology.

The objective of the proposed informal minisymposium is to foster connections between different European centers that concentrate on studies of biocatalysis at the molecular level of enzymes. The meeting especially aims to build contacts between young, PhD-student level researchers by providing them the possibility to discuss their results in an informal environment.

References:

Details

Date:
October 8 - 9, 2008
Place:
University of Oulu, Linnanmaa campus
Organization:

The Center of Expertise on Structure-based Biocatalysis Research Oulu (StruBioCat). This center is built around the common research interests of the following groups:

Confirmed Speakers:

  • Jörg Claren (University of Regensburg, Germany)

    De novo design of (βα)8-barrel enzymes with wild-type catalytic activity.

  • Matti Vaismaa (Department of Biochemistry, Oulu)

    The design, synthesis and evaluation of new substrate candidates based on triosephosphate isomerase.

  • Laura Salusjärvi (VTT, Espoo, Finland)

    Global analysis and approaches to enhance xylose metabolism in recombinant Saccharomyces cerevisiae.

  • Uwe Sauer (University of Umeå, Sweden)

    t.b.a.

  • Thomas Renger (FU Berlin, UNICAT cluster, Germany)

    Calculation of optical properties of pigments in proteins and non-polar solvents.

  • Nanna Alho (Department of Chemistry, University of Oulu)

    Utilization of NMR and MS techniques in biocatalysis research

  • Kathleen Szeker (TU Berlin and University of Oulu)

    High throughput methods for the production of thermostable enzymes

  • Mikko Salin (Department of Biochemistry, Oulu)

    Protein crystallographic characterisation of the A-TIM binding properties.

  • Satyan Sharma (Biocenter Oulu and Department of Biochemistry, Oulu, Finland)

    Eludicidation of enzyme reaction mechanism by theoretical approaches.

  • Marco Casteleijn

    Towards new biocatalytic activity of ATIM by structure based directed evolution

Program:
Schedule
Low Budget:
Please note that this minisymposium is a low budget meeting. There is coffee during the breaks, but no arrangements for travel, accommodation, and lunches will be made.

Registration

Registration is not any possible.